Summary
-
Treatment
should aim to reduce drug-related harm.
-
The
client's motivation to change the component behaviours of their drug
taking as well as their desire to achieve abstinence must inform the
treatment choices made.
-
Appropriate
treatment duration is a key factor in achieving positive outcomes.
-
The
indications for treatment should be carefully considered following
a thorough assessment.
-
Methadone
shall only be used in the treatment of people who are opium dependent
-
Prescribing
medication other than oral methadone mixture for the treatment of
opiate dependence is controversial and should normally be undertaken
only by a specialist service.
The
decision about what treatment to offer is based on:
- What
is available
- The
client's previous history
- The
client's current circumstances
and
the clinician's judgement of the required degree of:
- Structure
- Monitoring
and
- Support.
Introduction
Assessment allows
us to formulate ideas about what the client needs so we can begin to look
at the viability of the treatment options available. The treatment options
that can be offered will probably depend largely on what facilities exist
in your area as, with the exception of residential rehabilitation, funders
are unlikely to buy treatment from outside their area.
Treatment choice must
be guided by detailed assessment and clear treatment goals.
This section looks
in broad terms at two of the principles underlying methadone prescribing:
- Motivation and
change
- Harm reduction.
It then outlines:
- Treatment options
that are available
- Criteria for choosing
the optimum methadone treatment duration.
Motivation
and change
A model of understanding
drug-using behaviour and the process of changing it that is used by many
clinicians in the field to inform their practice is 'the stages of change'
model proposed by Prochaska and DiClimente.85
'Motivational interviewing'
is the name given to the use of interventions, designed using this model,
to help people achieve change in the component behaviours of their drug
dependence and/or abstinence. Many clinicians use other psycho-social
and counselling approaches to help clients resolve problems in all areas
of their life while using the stages of change model to understand the
processes the client is going through in terms of their drug use.
Most people who achieve
lasting change in any ingrained behaviour do not achieve it at their first
attempt. This is equally true for opiate use; most people who become lastingly
opiate free have been through a series of detoxifications and relapses
which finally result in a lasting abstinence.
It is possible to
learn from each unsuccessful attempt, and to use the lessons learned to
achieve better results in the future. The chances of success are higher
if someone has been through the process of stopping and starting again
than if they are stopping for the first time. For this reason it may be
more helpful to view the process as progressing along an upward spiral
rather than going round in circles.
Precontemplation:
'Problem, what problem?'
In this
stage the drug user has no concerns about their drug use. Other people
may have concerns and indeed the drug user may suffer all sorts of problems
as a result of the drug use - but not identify drugs as the cause.
This perception can
be reinforced by spending a lot of time with other drug users, thus rendering
the problems they experience as 'normal' or by rationalising 'everybody
takes something' or 'the people with a problem are the ones who are worse
than me'.
People in precontemplation
often benefit from the opportunity to get their drug use in perspective,
to understand which of their problems are drug-related and to understand
the reasons why they are using drugs.
If, to improve health
or to achieve other goals, we wish to change the drug-using behaviour
of a precontemplator, the initial aim is to enable them to weigh up the
pros and cons of their drug use and to recognise problems and to attribute
them accurately.
Contemplation:
'I'm not happy, but I'm not sure what to do'
People in
the contemplation stage are concerned about their drug use but are often
not sure what they can do - and may be ambivalent about whether or not
they want to do anything. This may result in huge changes in what someone
wants to do (and in their behaviour) from day to day.
It is in this stage,
as much as in relapse, that contemplators frustrate helpers with urgent
requests for help that are then not followed through. People may ask for
a detox one day, relapse only a few days into the programme and come back
a week later demanding an in-patient detox, but then fail to attend the
assessment interview.
At this stage clients
will benefit from help in understanding their predicament, coming to a
stable decision about what they want, and identifying strategies to achieve
it.
Action:
'I'm making changes'
It is at
this stage that people implement the strategies and make the changes in
their behaviour that they identified while contemplating change.
People spend the least
time in action: the strategies either fail and they go back to thinking
about change or they move on to maintenance. At this stage they need support,
encouragement and help to develop a sense of perspective: it can be an
emotionally fragile time.
Maintenance
of behaviour change
This is
an active state of holding on to the changes made. Complacency is the
main enemy of maintenance.
The (ex)drug user
may feel as if they have made it and fail to consider ways of holding
on to the changes they have made - or look for danger signs. The helping
services are often inclined to discharge the people in maintenance and
go back to dealing with the more demanding contemplators.
When in maintenance
people may benefit from help in identifying things that may go wrong,
access to help in dealing with problems before they get out of hand and
peer support from other people who are maintaining the same changes.
Relapse
This is
a common successor to maintenance. The following cues often precipitate
relapse:86
Negative mood states:
- Boredom
- Depression
- Anxiety
- Anger
Social situations:
- Other people using
drugs
- Offers of drugs
- Partners relapsing
- Unexpected problems
Associations:
- Flu
- Media mentioning
drugs
- People
- Places
- Money.
It can be useful to
work with clients to plan strategies for coping with relapse should it
occur, but this has to be done carefully to avoid discouraging the client
from attempting change.
Relapse need not be
an entirely negative event. Indeed since most people who sustain maintenance
have relapsed several times on their way, it is an important part of the
process. Worker and client should be clear that an attempt to withdraw
from drug use which ends in relapse is ultimately worthwhile as a step
towards lasting change.
The value of this
model is in reminding us that it is too simplistic to think of people
as motivated or unmotivated. People are at different stages of motivation
for different behaviours. It also puts into perspective (especially when
compared to dieting or smoking) the attempts to achieve huge changes such
as going from dependent drug use to abstinence.
Harm
reduction
Adjuncts
or alternatives to methadone treatment
A full menu
of services to support methadone treatment would include:
- In-patient detoxification
- In-patient assessment
- Out-patient lofexidine
detoxification
- Out-patient dihydrocodeine
or buprenorphine treatment
- Prescribing injectable
drugs
- Prescribing diamorphine
(heroin)
- Breathalysing facilities
- Supervised Antabuse
- HIV testing and
counselling
- Mental health services
- Counselling
- Psychotherapy
- Alternative therapies
- Employment advice
- Skills training
- Recreational activities
- Residential rehabilitation
- Supervised naltrexone
Important as all of
these can be in supporting and enhancing the outcome of methadone treatment,
many of them are, unfortunately, beyond the scope of this briefing and
so cannot be described in detail.
Treatment
aims
Before 1986
very often the only treatment aim on offer was abstinence. Even today
many members of the helping professions are ambivalent about their role
in working with drug users and feel (like some ex drug users) that the
only 'real' treatment goal is abstinence.
Proponents of harm
reduction are aiming at abstinence, as an ultimate goal, for most of their
clients. The key to effective treatment is in the time scale that is envisaged
before this goal can be reached, and the services that are offered to
the drug user in the period before they are ready and/or able to achieve
abstinence.
Methadone can be used
in a number of ways to help people reduce their drug-related harm and
to help them towards abstinence.
Justifiable aims for
a methadone prescription would include achieving sustained contact with
services that can offer the following:
- Advice and information
on HIV and hepatitis
- Safer drug-using
advice
- Safer injecting
advice
- Counselling
- Support, etc.
and:
- Cessation of injecting
- Significant reduction
in illicit drug use
- Reduction of high
risk behaviour to acquire/take drugs
- Increased stability
in drug use
- Reduced crime
- Improvement of
relationships
- Cessation of heroin
use
- Cessation of other
drug use
- Ability to maintain
or gain employment
- Ability to maintain
or start a college course
- Reduction in drug
use
- Detoxification
and abstinence.
Is
prescribing methadone appropriate?
Methadone treatment
may be justified if the following criteria are met:
- The client is a
non-injector who has been opiate dependent for more than 6 months
- The client is opiate
dependent and injecting opiates
and methadone:
- Is not going to
increase drug-related harm
- Will help achieve
appropriately set short and long-term aims from the list above.
However methadone
is not an innocuous treatment and inappropriate methadone prescribing
can:
- Cause fatal overdose
- Simply increase
a person's total drug consumption
- Increase the drug-related
chaos in a person's life
- Supply the illicit
market
- Demoralise prescribing
and other staff
- Reduce respect
for the prescribing agency among both drug users and other helping agencies
- Reduce the client's
motivation and ability to achieve abstinence
- Create opiate dependence.
Other
reasons why someone might ask for a methadone prescription
Treatment
of opiate use does not begin and end with methadone. Where people are
not using opiates daily, or if they are using very low doses, medical
treatments may be of very low priority. Not everyone who presents requesting
a methadone prescription is a bona fide opiate dependent looking for help
in changing their drug use. Other reasons might include their wanting
the following:
- A 'status symbol'
- a methadone prescription is certification of being a 'junkie'
- A source of income
to buy heroin
- Something to exchange
for heroin
- A way of keeping
a partner with a more serious heroin problem stable
- Help with their
drug problem, believing that having a methadone prescription is the
only way to get help.
Or they may be seeking
a methadone prescription because they have been coerced by a:
- Relative
- Friend
- Partner
- Employer
- Court.
Determining
optimum treatment duration
The initial
care plan should outline the anticipated duration of treatment. Clearly
this can be modified over time but an agreement should be reached at the
outset which outlines either the:
- Planned treatment
duration, or
- Intervals at which
it will be reviewed.
In 1990 the World
Health Organisation convened a special meeting of international experts
on methadone treatment and this group suggested a standard terminology
for methadone treatment using these terms:
- Short-term detoxification:
decreasing doses over one month or less
- Long-term detoxification:
decreasing doses over more than one month
- Short-term maintenance:
stable prescribing over 6 months or less
- Long-term maintenance:
stable prescribing over more than 6 months.
The indications and
contra-indications for these four categories are set out below.
Short-term
detoxification
See also Section
9: Methadone detoxification.
Decreasing
doses over one month or less
If methadone
treatment is justified a minimum definition of successful short-term detox
would be:
- Contact with helping
services during the treatment period
- No illicit opiate/depressant
drug use during the detoxification period
- No opiate use for
1 month following detox.
Factors
that would indicate that short-term detox may be a successful treatment
option |
Factors
that would indicate that short-term detox may not be a successful
intervention |
Strong
motivation to become drug-free |
Little
motivation to become drug-free |
Strong
social support network |
Poor
social support network |
Short
history of opiate use |
Long
history of continuous opiate use |
Low
daily opiate use |
High
daily opiate use |
High
degree of control in opiate use |
Low
degree of control in opiate use |
No
other drugs being used |
Poly
drug use e.g. opiates, alcohol, benzodiazepines, etc. |
Client
requesting this treatment option of their own free will |
Pressure
from others to undergo treatment despite reluctance and anxiety |
Client
has a clear vision of what they are aiming for and of the benefits
of being drug-free |
Client
only wants to be 'off opiates' and has not considered how to stay
off |
Availability
of in-patient detox facility |
Early
or late pregnancy |
Detox
is part of a care plan which includes residential rehabilitation |
Unavailability
of in-patient detox facility |
Client
is smoking rather than injecting opiates |
Compulsory
detox following breach of prescribing contract |
Long-term
detoxification
Long-term
detox regimes are seldom the optimum treatment option, to read an additional
piece on long-term detox written for this online edition of the book,
please click here.
See also Section
9: Methadone detoxification.
Decreasing
doses over more than one month
If methadone
treatment is justified, and short-term detox has been excluded, a minimum
definition of successful long-term detox would be:
- Contact with helping
services during the treatment period
- No illicit opiate/depressant
drug use during the detoxification period
- No opiate use for
1 month following detox.
Factors
that would indicate that long-term detox may be a successful treatment
option |
Factors
that would indicate that long-term detox may not be a successful intervention |
Client
determination to become drug-free with a recognition that other factors
(physical, social, psychological) need working on as a pre-condition
to successful outcome of the detox |
Client
requests to become drug-free without recognition of the factors which
may cause relapse |
Failure
of short-term detox: particularly if withdrawal symptoms precipitate
relapse |
Long-standing
chaotic, drug-using lifestyle |
Client
request for long-term detox |
Little
motivation to become drug-free |
Desire
to address psychological issues during the detox period |
No
desire to address psychological issues that may contribute to relapse |
Social
support system in place or that can be rebuilt by the end of the detox |
No
prospect of a social support network developing during the detox |
Need
and desire to stop injecting behaviour in addition to detoxing |
Desire
to use injected drugs in a controlled way following detox |
Support
available from a specialist and/or counselling drug service |
No
support available from a specialist drug and/or counselling service |
Short-term
maintenance
Stable
prescribing over 6 months or less
If methadone
treatment is justified, and short and long-term detox have been excluded
as options, a minimum definition of successful short-term maintenance
would be:
- Contact with helping
services during the treatment period
- Maintenance of
contact with services
- Cessation of high-risk
injecting behaviour
- Reduction/cessation
of other opiate and depressant drug use.
Factors
that would indicate that short-term maintenance may be a successful
treatment option |
Factors
that would indicate that short-term maintenance may not be a successful
intervention |
Continued
opiate use following past short and/or long-term detoxes |
Long-term,
chaotic drug-using history |
Client
request for short-term maintenance |
Long-term
injecting drug use |
Opiate
use following or during detox |
Previous
failure of detox following short-term maintenance |
Prospect
of social, physical and psychological factors improving given a period
of drug-using stability |
Client
cannot envisage an end to their drug use |
Client
desire to work at creating pre-conditions to successful detox |
Client
feels dependent on injecting |
Client
has no dependence on injecting |
Intravenous
drug use which has, in the past, proved difficult to stop |
Support
available from a specialist drug service |
No
support available from a specialist drug service |
Long-term
maintenance
Stable
doses over more than 6 months
If methadone
treatment is justified, and short and long-term detox and short-term maintenance
have been excluded as options, a minimum definition of successful long-term
maintenance would be:
- Contact with helping
services during the treatment period
- Maintenance of
contact with services
- Cessation of high-risk
injecting behaviour
- Reduction/cessation
of other opiate and depressant drug use.
Factors
that would indicate that long-term maintenance may be an appropriate
intervention |
Factors
that would indicate that long-term maintenance may not be a appropriate
intervention |
Long-term
history of drug use (particularly if injecting) |
Short-term
history of opiate use |
Successful
outcome of short-term maintenance but client still not ready to detox |
Client
has no desire to stabilise drug taking and poly drug use is continuing |
Poor
social support network |
No
previous histroy of methadone prescribing/detox |
Client
needs time to make considerable social or psychological changes in
order to be able to successfully detox |
Client
is apparently able and willing to reduce methadone consumption |
Support
available from a specialist drug service |
No
support available from a specialist drug service |
Treatment
setting
For more information
on the services available see Section 1: The
history of methadone prescribing - Services available in the UK today.
This section looks at the areas to which each treatment setting is best
and least suited in the context of making appropriate treatment choices.
Specialist
centre prescribing
Specialist
centres are usually most suited to managing:
- Large numbers of
clients who could overwhelm smaller services
- Chaotic drug users
who need high levels of supervision and support
- Difficult to manage
clients who require treatment from specialised staff - such as clients
with multiple drug use or concurrent mental health problems.
They are usually less
suited to helping:
- People who work
full time (if they are only open Monday-Friday, 9am-5pm)
- Rural areas with
poor public transport
- Opiate users not
part of the subculture
- People who are
ambivalent about receiving help (they often have long waiting lists).
GPs
prescribing alone
General
practitioners working without the support of a consultant with a special
interest in drugs or a community drug team are usually most suited to
managing people who:
- They know
- Require short or
medium-term detoxification
- Have no concurrent
benzodiazepine or other drug dependence
- Are able to attend
appointments and are otherwise stable.
They are less suited
to prescribing for people who:
- Are temporary residents
- Are chaotic in
their drug use and lifestyle
- Require maintenance
prescribing
- Have a dependence
on other drugs in addition to opiates.
GPs
working with a community drug team
With specialist
support from clinicians who can have regular contact with the client over
and above their 5-10 minute weekly or fortnightly consultation, GPs can
take on and treat a much wider range of clients who have drug problems.
They are usually best suited for clients who:
- Are stable enough
to deal with attending appointments on time
- Would find attending
a specialist centre difficult
- Are on a stable
methadone programme - either detoxing or maintenance.
They are usually less
suited for people who:
- Are chaotic and
find attending appointments difficult
- Require supervised
consumption of their methadone.
Private
practice
Standards
in private practice probably vary more than in other types of service
for opiate users. Although all the questions below are legitimate questions
to ask of any service if you are referring to, or receiving a client from,
a private practice the following questions will help you ascertain the
type and quality of the service on offer:
- Is it a group or
single-handed practice?
- Have the staff
recieved training in drug dependence?
- Are there written
prescribing policies?
- What are the methadone
collection regimes?
- What is the degree
of contact and supervision of clients?
- Are counsellors
and psychological support available and part of the treatment?
- Is there any liaison
with the local statutory service and contact with the drug unit consultants?
- Are there limits
on dosage and formulation?
- How is dosage calculated?
- What is the referral
procedure?
- Is there a waiting
list?
- What is the assessment
procedure?
- What is the average
case load per clinician?
- Are Home Office
guidelines followed, such as requesting proof of a client's ability
to fund their consultation and pharmacy fees?
- What is the catchment
area of the practice?
- What are the fees
and do they include, urinalysis as well as the consultation, and counselling?
- Are general practitioners
kept informed?
- What information
is given on treatment issues such as HIV and AIDS?
In general, responsible,
well-supported and informed private practitioners are best suited for
prescribing to people who:
- Are in full-time,
well-paid employment
- Have legitimate
access to funds to pay for treatment
- Are stable
- Will benefit from
treatment not normally available on the NHS, such as injectables.
They are less suited
to prescribing for people who:
- Have no legitimate
access to funds
- Are chaotic and
seeking maximum possible prescribed medication for least contact with
helping services.
Prescribing
injectable methadone
There are strong
arguments for and against the principle of prescribing injectable methadone
which are set out below.
Arguments
used for prescribing injectable methadone |
Arguments
used against prescribing injectable methadone |
It
is an incentive for people who may not attend a service offering only
oral methadone |
It
is difficult to determine who will benefit from prescribed injectables
as there is no clear research or guidelines |
It
is an opportunity to work on a harm reduction basis with people who
might not otherwise be in treatment |
People
may have stabilised well (and with less harm) on oral medication |
It
is a realistic prescribing response to people who cannot stop injecting |
If
decisions are made on prescribers� preferences � in the absence of
guidelines � it will be a constant source of conflict |
It
may attract users into treatment earlier in their career |
Clinicians
can feel more like legal dealers and could attract more people than
they could cope with into services |
Giving
clients a menu of drug choices can be empowering |
Giving
clients more choice can reduce the therapeutic value of services and
leave clinicians feeling de-skilled |
It
can provide a way of stopping using intravenous heroin |
It
can cultivate or perpetuate injecting behaviour |
It
is a useful addition to an oral methadone prescription if occasional
injecting behaviour persists |
It
can be seen as doctors approving of, and colluding with, dangerous
behaviour |
It
could be cost effective if it prevents people from catching HIV |
It
may be seen by politicians and the media as 'being soft' on drugs
and provide the springboard for a backlash that could threaten all
prescribing |
|
Injectables
on the illicit market would be even more dangerous than methadone
mixture |
If, having considered
the pros and cons of prescribing injectables, a service has decided to
offer injectable methadone as a treatment option, the indications and
contra-indications are set out below.
Factors
that would indicate that prescribing injectable methadone may be an
appropriate intervention
|
Factors
that would indicate that prescribing injectable methadone may not
be an appropriate intervention |
Client
continuing to inject illicit opiate drugs despite 6 months or more
on over 80mg oral methadone daily |
Client
has no experience of oral methadone treatment |
Long
history of injecting |
Short
history of injecting |
Client
only injecting opiates in addition to their methadone |
Client
injecting many drugs in addition to taking their oral methadone |
Client
has long-term contact with the drug service |
Client
is a new referral or temporary resident |
Diamorphine
prescribing
As with the
prescription of injectables there are strong arguments for and against
the principle of prescribing the user's drug of choice which are set out
below.
Arguments
used for prescribing diamorphine (heroin) |
Arguments
used against prescribing diamorphine (heroin) |
Heroin,
especially if smoked, is less likely to cause accidental overdose
than methadone |
As
opiate users who are more chaotic are attracted into services there
is more likelihood that the prescribed drugs will just increase the
total drug consumption |
It
would attract many of the people who are most at risk of HIV and other
drug-related harm into contact with drug services |
The
number of people who would request treatment with heroin could overwhelm
services |
This
is a catch 22 situation: while �the establishment� opposes heroin
prescribing, research funding is not available to prove the improved
efficacy its proponents expect |
There
is little research to demonstrate that it would be an effective intervention |
It
is for clinicians to inform policy makers of the most effective forms
of health care: reduced crime and HIV spread are easy positive outcomes
to �sell� to opponents of prescribing |
As
with prescribing injectables, prescribing heroin could provide the
basis for a reactionary backlash against all prescribing and services
for drug users |
The prescribing of
diamorphine in the treatment of dependence is restricted to those doctors
who have a Home Office licence to do so. If, having considered the pros
and cons of prescribing diamorphine, a service has decided to offer it
as a treatment option, the indications and contra-indications are set
out below.
Arguments
used for prescribing diamorphine (heroin) |
Arguments
used against prescribing diamorphine (heroin) |
Factors
that may indicate that prescribing diamorphine would be an appropriate
intervention |
Factors
that may indicate that prescribing diamorphine may not be an appropriate
intervention |
Heroin
has been the drug of choice over a long period of time |
Client
also injects drugs other than heroin on a regular basis |
Client
has a long history of injecting |
Client
has a short history of injecting |
Client
has continued to inject heroin regularly in addition to taking oral
methadone |
Client
occasionally injects opiates in addition to taking oral methadone |
Client
has continued injecting despite receiving 80mg or more of methadone
for more than 6 months |
Client
has continued injecting on a low dose of oral methadone |
Client
has long-term contact with the service |
Client
is new to the service or a temporary resident |
Additional
risk from injecting practice due to HIV-positive status |
Client
is reluctant to engage with the service and a diamorphine prescription
is unlikely to improve this |
Client
is already on a diamorphine prescription |
|
|